肺癌にまたまた融合遺伝子 (Cell12月号)

Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer

Cell, Vol 131, 1190-1203, 14 December 2007

この図がすべて

(C) Schematic representation of the EML4, ALK, and EML4-ALK fusion proteins. Arrow indicates the chromosomal breakpoint.
(D) Schematic representation of the TFG, ALK, and TFG-ALK fusion proteins. Arrow indicates the chromosomal breakpoint.
(E) Schematic representation of the SLC34A2, ROS, and SLC34A2-ROS fusion proteins. Arrow indicates the chromosomal breakpoint.
(F) Schematic representation of the CD74, ROS, and CD74-ROS fusion proteins. Arrow indicates the chromosomal breakpoint.

このうち最初のEML4-ALK は自治医の間野さんところからこの８月に出たもの(Nature)、大腸癌も負けられません！