今週号のPNAS：乳癌論文10連発

• (1)
  
  

  • Ana M. Mendes-Pereira,
  • David Sims,
  • Tim Dexter,
  • Kerry Fenwick,
  • Ioannis Assiotis,
  • Iwanka Kozarewa,
  • Costas Mitsopoulos,
  • Jarle Hakas,
  • Marketa Zvelebil,
  • Christopher J. Lord,
  • and Alan Ashworth

  Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen

  PNAS 2012 109 (8) 2730-2735; published ahead of print April 11, 2011, doi:10.1073/pnas.1018872108
  
  
  

• (2)
  
• Kideok Jin,
• • Xiangjun Kong,
  • Tariq Shah,
  • Marie-France Penet,
  • Flonne Wildes,
  • Dennis C. Sgroi,
  • Xiao-Jun Ma,
  • Yi Huang,
  • Anne Kallioniemi,
  • Goran Landberg,
  • Ivan Bieche,
  • Xinyan Wu,
  • Peter E. Lobie,
  • Nancy E. Davidson,
  • Zaver M. Bhujwalla,
  • Tao Zhu,
  • and Saraswati Sukumar

  The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway

  PNAS 2012 109 (8) 2736-2741; published ahead of print June 20, 2011, doi:10.1073/pnas.1018859108

• (3)
  
• James M. Haughian,
• Mauricio P. Pinto,
• J. Chuck Harrell,
• Brian S. Bliesner,
• Kristiina M. Joensuu,
• Wendy W. Dye,
• Carol A. Sartorius,
• Aik Choon Tan,
• Päivi Heikkilä,
• Charles M. Perou,
• and Kathryn B. Horwitz

• Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch

  PNAS 2012 109 (8) 2742-2747; published ahead of print October 3, 2011, doi:10.1073/pnas.1106509108
  
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• (4)
• Samantha R. Oakes,
• François Vaillant,
• Elgene Lim,
• Lily Lee,
• Kelsey Breslin,
• Frank Feleppa,
• Siddhartha Deb,
• Matthew E. Ritchie,
• Elena Takano,
• Teresa Ward,
• Stephen B. Fox,
• Daniele Generali,
• Gordon K. Smyth,
• Andreas Strasser,
• David C. S. Huang,
• Jane E. Visvader,
• and Geoffrey J. Lindeman

• Sensitization of BCL-2–expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737

  PNAS 2012 109 (8) 2766-2771; published ahead of print July 18, 2011, doi:10.1073/pnas.1104778108
  
  
  
• (5)
  Patricia J. Keller,
• • Lisa M. Arendt,
  • Adam Skibinski,
  • Tanya Logvinenko,
  • Ina Klebba,
  • Shumin Dong,
  • Avi E. Smith,
  • Aleix Prat,
  • Charles M. Perou,
  • Hannah Gilmore,
  • Stuart Schnitt,
  • Stephen P. Naber,
  • Jonathan A. Garlick,
  • and Charlotte Kuperwasser

  Defining the cellular precursors to human breast cancer

  PNAS 2012 109 (8) 2772-2777; published ahead of print September 21, 2011, doi:10.1073/pnas.1017626108
  
  
  

  • (6)
  • 
    
  • Sarah J. Conley,
  • Elizabeth Gheordunescu,
  • Pramod Kakarala,
  • Bryan Newman,
  • Hasan Korkaya,
  • Amber N. Heath,
  • Shawn G. Clouthier,
  • and Max S. Wicha

  Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

  PNAS 2012 109 (8) 2784-2789; published ahead of print January 23, 2012, doi:10.1073/pnas.1018866109
  
  
  

  • (7)
  • 
    
  • Vessela N. Kristensen,
  • Charles J. Vaske,
  • Josie Ursini-Siegel,
  • Peter Van Loo,
  • Silje H. Nordgard,
  • Ravi Sachidanandam,
  • Therese Sørlie,
  • Fredrik Wärnberg,
  • Vilde D. Haakensen,
  • Åslaug Helland,
  • Bjørn Naume,
  • Charles M. Perou,
  • David Haussler,
  • Olga G. Troyanskaya,
  • and Anne-Lise Børresen-Dale

  Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling

  PNAS 2012 109 (8) 2802-2807; published ahead of print September 9, 2011, doi:10.1073/pnas.1108781108
  
  
  

  • (8)
  • 
    
  • Richard Marcotte,
  • Harvey W. Smith,
  • Virginie Sanguin-Gendreau,
  • Rosalie V. McDonough,
  • and William J. Muller

  Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis

  PNAS 2012 109 (8) 2808-2813; published ahead of print May 31, 2011, doi:10.1073/pnas.1018861108
  
  
  

  • (9)
  • 
    
  • Reo Maruyama,
  • Michail Shipitsin,
  • Sibgat Choudhury,
  • Zhenhua Wu,
  • Alexei Protopopov,
  • Jun Yao,
  • Pang-Kuo Lo,
  • Marina Bessarabova,
  • Alex Ishkin,
  • Yuri Nikolsky,
  • X. Shirley Liu,
  • Saraswati Sukumar,
  • and Kornelia Polyak

  Altered antisense-to-sense transcript ratios in breast cancer

  PNAS 2012 109 (8) 2820-2824; published ahead of print November 22, 2010, doi:10.1073/pnas.1010559107
  
  
  

  • (10)
  • 
    
  • Stefano Volinia,
  • Marco Galasso,
  • Maria Elena Sana,
  • Timothy F. Wise,
  • Jeff Palatini,
  • Kay Huebner,
  • and Carlo M. Croce

  Breast cancer signatures for invasiveness and prognosis defined by deep sequencing of microRNA

  PNAS 2012 109 (8) 3024-3029; published ahead of print February 6, 2012, doi:10.1073/pnas.1200010109